Journal of Traditional Chinese Medicine ›› 2022, Vol. 42 ›› Issue (4): 487-492.DOI: 10.19852/j.cnki.jtcm.2022.04.001
• Systematic Reviews • Next Articles
DING Lijuan, YIN Lu(), WANG Liping, SUN Yaya, LIU Xiaoyun, LI Xiangrong
Received:
2021-04-16
Accepted:
2021-07-22
Online:
2022-08-15
Published:
2022-07-12
Contact:
YIN Lu
About author:
YIN Lu, Medical Research & Biometrics Center, National Center for Cardiovascular Diseases, Beijing 102300, China. yinlu@mrbc-nccd.com, Telephone: +86-13691166577DING Lijuan, YIN Lu, WANG Liping, SUN Yaya, LIU Xiaoyun, LI Xiangrong. Effectiveness of redcore lotion in patients with vulvovaginal candidiasis: a systematic review and Meta-analysis[J]. Journal of Traditional Chinese Medicine, 2022, 42(4): 487-492.
Study | Study cities (study period) | Pregnant (%) | Redcore lotion + Miconazole | Miconazole alone | Drug dosage, MOAa | Treatment (days) | Jadad scores | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. | Age (years) | ORR (%) | AE (%) | No. | Age (years) | ORR (%) | AE (%) | Honghe | Miconazole | |||||||||
Liu HN et al 2009 | Zhengzhou (2005-2008) | 100 | 50 | 24-34 | 98.0 | NA | 50 | 22-35 | 86.0 | NA | 10 mL, bid | 0.4 g, qd | 3 | 2 | ||||
Jia XW et al 2010 | Xi’an (2009-2010) | 0 | 43 | 36.6±7.3 | 100.0 | NA | 43 | 35.8±7.6 | 97.7 | NA | 10 mL, qd | 0.4 g, qd | 3 | 2 | ||||
Fan KL 2014 | Xi’an (NA) | 0 | 100 | 20-67 | 97.0 | 2.0 | 100 | 20-67 | 88.0 | 7.0 | 10 mL, qd | 0.2 g, qd | 7 | 1 | ||||
Sun YF et al 2015 | Hangzhou (2012-2014) | 100 | 77 | 26.7±2.7 | 98.7 | 3.9 | 77 | 25.8±2.8 | 71.4 | 6.5 | 10 mL, tid | 0.2 g, qd | 7 | 2 | ||||
Li YL 2017 | Lingyuan (2015-2016) | 100 | 46 | 26.9±3.2 | 97.8 | NA | 46 | 26.2±3.4 | 76.1 | NA | 10 mL, tid | 0.2 g, qd | 7 | 2 | ||||
Yu YH 2017 | Jingdezhen (2016-2017) | 66.7 | 21 | 29.0±1.2 | 95.2 | 4.8 | 21 | 31.0±1.5 | 71.4 | 38.1 | 10 mL, bid | 0.2 g, qd | 7 | 2 | ||||
Wang JM 2018 | Bayan Nur \(2016-2017) | 100 | 47 | 25.9±3.4 | 98.0 | 4.0 | 47 | 25.9±3.5 | 72.0 | 18.0 | 10 mL, bid | 0.2 g, qd | 7 | 2 |
Table 1 Characteristics of the included studies
Study | Study cities (study period) | Pregnant (%) | Redcore lotion + Miconazole | Miconazole alone | Drug dosage, MOAa | Treatment (days) | Jadad scores | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. | Age (years) | ORR (%) | AE (%) | No. | Age (years) | ORR (%) | AE (%) | Honghe | Miconazole | |||||||||
Liu HN et al 2009 | Zhengzhou (2005-2008) | 100 | 50 | 24-34 | 98.0 | NA | 50 | 22-35 | 86.0 | NA | 10 mL, bid | 0.4 g, qd | 3 | 2 | ||||
Jia XW et al 2010 | Xi’an (2009-2010) | 0 | 43 | 36.6±7.3 | 100.0 | NA | 43 | 35.8±7.6 | 97.7 | NA | 10 mL, qd | 0.4 g, qd | 3 | 2 | ||||
Fan KL 2014 | Xi’an (NA) | 0 | 100 | 20-67 | 97.0 | 2.0 | 100 | 20-67 | 88.0 | 7.0 | 10 mL, qd | 0.2 g, qd | 7 | 1 | ||||
Sun YF et al 2015 | Hangzhou (2012-2014) | 100 | 77 | 26.7±2.7 | 98.7 | 3.9 | 77 | 25.8±2.8 | 71.4 | 6.5 | 10 mL, tid | 0.2 g, qd | 7 | 2 | ||||
Li YL 2017 | Lingyuan (2015-2016) | 100 | 46 | 26.9±3.2 | 97.8 | NA | 46 | 26.2±3.4 | 76.1 | NA | 10 mL, tid | 0.2 g, qd | 7 | 2 | ||||
Yu YH 2017 | Jingdezhen (2016-2017) | 66.7 | 21 | 29.0±1.2 | 95.2 | 4.8 | 21 | 31.0±1.5 | 71.4 | 38.1 | 10 mL, bid | 0.2 g, qd | 7 | 2 | ||||
Wang JM 2018 | Bayan Nur \(2016-2017) | 100 | 47 | 25.9±3.4 | 98.0 | 4.0 | 47 | 25.9±3.5 | 72.0 | 18.0 | 10 mL, bid | 0.2 g, qd | 7 | 2 |
Figure 1 Forest plots for r treatment effect of redcore lotion plus miconazole vs miconazole alone A: vulvovaginal candidiasis cure rate; B: fungal culture negative rate; C: effective rate. Redcore lotion plus miconazole vs miconazole alone.
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